The Endocannabinoid System

Cannabis has an amazing influence on the human body and this is because of our endocannabinoid system. This system consists of a series of receptors that are configured  to accept only cannabinoids.

Cannabinoids are a group of chemical compounds found in the cannabis plant. Two examples of cannabinoids would be THC and CBD. Cannabinoids found naturally in the body are called endocannabinoids. ‘Endo’ stands for endogenous, meaning within the body.

The two known cannabinoid receptors we have are called Cannabinoid Receptor 1 (CB1) and Cannabinoid Receptor 2 (CB2). Both are found throughout the body. When cannabinoids activate CB1 or CB2 receptors, they change the way the body functions.

Research shows that THC is specifically keyed to the CB1 receptor so this means it is responsible for the psychoactive effects. Its most important effect is its ability to moderate the perception of pain. The Intensity of the pain feelings is reduced when THC is present in the CB1 site.

The CB2 receptors are keyed to CBD which has anti-inflammatory and anti-spasmodic qualities. Another effect of CBD is that it reduces the effects of THC. It actually cancels the THC from the CB1 receptor. This is a good way to help anyone that suffers the short term side effects of THC like paranoia or anxiety. Some CBD will help calm those unwanted feelings.




The main job of the endocannabinoid system is to promote homeostasis. Homeostasis is the body’s attempt to maintain a constant and balanced internal environment. It controls and regulates pain, appetite, inflammation, sleep and cell metabolism. When the body does not produce enough endocannabinoids or cannot regulate them properly this can cause disruption to multiple systems in the body leading to illness.

The fact that we have a system in our body that produces cannabinoids, and is specifically designed to accept them, should be more than enough proof that cannabis is medicine yet medical schools don’t teach it and most doctors have never heard of our endocannabinoid system. Natural cannabinoids keep you healthy and happy. This piece of information doesnt even scratch the surface on the abilities of the cannabis plant and our endocannabinoid system.   To find out more click here.


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